Rhabdomyolysis is a complex medical condition involving the rapid dissolution of damaged or injured skeletal muscle. This disruption of skeletal muscle integrity leads to the direct release of intracellular muscle components, including myoglobin, creatine kinase aldolase, and lactate dehydrogenase, as well as electrolytes, into the bloodstream and extracellular space. Rhabdomyolysis ranges from an asymptomatic illness with elevation in the CK level to a life-threatening condition associated with extreme elevations in CK, electrolyte imbalances, acute renal failure and disseminated intravascular coagulation
people who work out and the push their self this what happen Rhabdomyolysis is the breakdown of muscle tissue that leads to the release of muscle fiber contents into the blood. These substances are harmful to the kidney and often cause kidney damage. Symptoms include dark, reddish urine, a decreased amount of urine, weakness, and muscle aches. rhabdomyolysis is confirmed by detecting elevated muscle enzymes in blood, which include creatine phosphokinase Early treatment with aggressive fluid replacement reduces the risk of kidney damage. Treatment with intravenous (IV) fluids helps maintain urine production and prevent kidney failure. Rarely, dialysis treatment may be needed to help your kidneys filter waste products while they are recovering Rhabdomyolysis is the rapid destruction of skeletal muscle resulting in leakage into the urine of the muscle protein myoglobin. Rhabdomyolysis has many causes. Medications can cause muscle injury and rhabdomyolysis. Rhabdomyolysis can cause muscle pain and weakness. Rhabdomyolysis is the breakdown of damaged skeletal muscle.Muscle breakdown causes the release of myoglobin into the bloodstream. Myoglobin is the protein that stores oxygen in your muscles. If you have too much myoglobin in your blood it can cause kidney damage. https://medlineplus.gov/ency/article/000473.htm |